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GTPBP3 Full-Length MS Protein Standard

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Product Description


NameGTPBP3 Full-Length MS Protein Standard
Cat#CPFL300836
Protein NameGTP binding protein 3 (mitochondrial)
SymbolGTPBP3
SynonymsCOXPD23; GTPBG3; MSS1; MTGP1; THDF1
AccessionNM_032620
Cytogenetic19p13.11
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGTPBP3 Full-Length MS Protein Standard (NP_116009), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.

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