TGIF2 Full-Length MS Protein Standard


Product Description:

Name TGIF2 Full-Length MS Protein Standard
Cat# CPFL300773
Protein NameTGFB-induced factor homeobox 2
SymbolTGIF2
SynonymsTGFB-induced factor 2; TGFB-induced factor homeobox 2
AccessionNM_021809
Cytogenetic20q11.23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW25.7 kDa
Expression TrueORF CloneRC200773
DescriptionTGIF2 Full-Length MS Protein Standard (NP_068581), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene.

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