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NCF2 Full-Length MS Protein Standard

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Product Description


NameNCF2 Full-Length MS Protein Standard
Cat#CPFL300704
Protein Nameneutrophil cytosolic factor 2
SymbolNCF2
SynonymsNCF-2; NOXA2; P67-PHOX; P67PHOX
AccessionNM_000433
Cytogenetic1q25
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionNCF2 Full-Length MS Protein Standard (NP_000424), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.

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