PFKM Full-Length MS Protein Standard


Product Description:

Name PFKM Full-Length MS Protein Standard
Cat# CPFL300702
Protein NameFructose-6-Phosphate Kinase
SymbolPFKM
SynonymsATP-PFK; GSD7; PFK-1; PFK1; PFKA; PFKX; PPP1R122
AccessionNM_000289
Cytogenetic12q13.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW85 kDa
Expression TrueORF CloneRC200702
DescriptionPFKM Full-Length MS Protein Standard (NP_000280), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.

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