PGAM2 Full-Length MS Protein Standard


Product Description:

Name PGAM2 Full-Length MS Protein Standard
Cat# CPFL300701
Protein Namephosphoglycerate mutase 2 (muscle)
SymbolPGAM2
SynonymsGSD10; PGAM-M; PGAMM
AccessionNM_000290
Cytogenetic7p13-p12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW28.6 kDa
Expression TrueORF CloneRC200701
DescriptionPGAM2 Full-Length MS Protein Standard (NP_000281), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X.

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