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FLI1 Full-Length MS Protein Standard

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Product Description


NameFLI1 Full-Length MS Protein Standard
Cat#CPFL300695
Protein NameFriend leukemia virus integration 1
SymbolFLI1
SynonymsEWSR2; SIC-1
AccessionNM_002017
Cytogenetic11q24.1-q24.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionFLI1 Full-Length MS Protein Standard (NP_002008), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.

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