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TCP1 Full-Length MS Protein Standard

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Product Description


NameTCP1 Full-Length MS Protein Standard
Cat#CPFL300686
Protein Namet-complex 1
SymbolTCP1
SynonymsCCT-alpha; CCT1; CCTa; D6S230E; TCP-1-alpha
AccessionNM_030752
Cytogenetic6q25.3-q26
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionTCP1 Full-Length MS Protein Standard (NP_110379), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found.

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