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MAGEA8 Full-Length MS Protein Standard

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Product Description


NameMAGEA8 Full-Length MS Protein Standard
Cat#CPFL300670
Protein Namemelanoma antigen family A, 8
SymbolMAGEA8
SynonymsCT1.8; MAGE8
AccessionNM_005364
CytogeneticXq28
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionMAGEA8 Full-Length MS Protein Standard (NP_005355), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Multiple alternatively spliced variants, encoding the same protein, have been identified.

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