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PAX8 Full-Length MS Protein Standard

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Product Description


NamePAX8 Full-Length MS Protein Standard
Cat#CPFL300651
Protein Namepaired box 8
SymbolPAX8
SynonymsOTTHUMP00000158659; OTTHUMP00000158660; paired domain gene 8; paired box 8
AccessionNM_003466
Cytogenetic2q13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionPAX8 Full-Length MS Protein Standard (NP_003457), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.

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