DLD Full-Length MS Protein Standard


Product Description:

Name DLD Full-Length MS Protein Standard
Cat# CPFL300639
Protein NameLipoamide Dehydrogenase
SymbolDLD
SynonymsDLDD; DLDH; E3; GCSL; LAD; PHE3
AccessionNM_000108
Cytogenetic7q31-q32
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW50.1 kDa
Expression TrueORF CloneRC200639
DescriptionDLD Full-Length MS Protein Standard (NP_000099), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants.

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