NCBP1 Full-Length MS Protein Standard


Product Description:

Name NCBP1 Full-Length MS Protein Standard
Cat# CPFL300630
Protein Namenuclear cap binding protein subunit 1, 80kDa
SymbolNCBP1
SynonymsCBP80; NCBP; Sto1
AccessionNM_002486
Cytogenetic9q34.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW91.7 kDa
Expression TrueORF CloneRC200630
DescriptionNCBP1 Full-Length MS Protein Standard (NP_002477), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5 cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.

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