LDOC1 Full-Length MS Protein Standard


Product Description:

Name LDOC1 Full-Length MS Protein Standard
Cat# CPFL300543
Protein Nameleucine zipper, down-regulated in cancer 1
SymbolLDOC1
SynonymsBCUR1; Mar7; Mart7
AccessionNM_012317
CytogeneticXq27
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW16.8 kDa
Expression TrueORF CloneRC200543
DescriptionLDOC1 Full-Length MS Protein Standard (NP_036449), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

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