PCOLCE Full-Length MS Protein Standard


Product Description:

Name PCOLCE Full-Length MS Protein Standard
Cat# CPFL300515
Protein Nameprocollagen C-endopeptidase enhancer
SymbolPCOLCE
SynonymsPCPE; PCPE-1; PCPE1
AccessionNM_002593
Cytogenetic7q22
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW47.8 kDa
Expression TrueORF CloneRC200515
DescriptionPCOLCE Full-Length MS Protein Standard (NP_002584), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity.

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