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CDC25A Full-Length MS Protein Standard

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Product Description


NameCDC25A Full-Length MS Protein Standard
Cat#CPFL300496
Protein NameCDC25A cell division cycle 25 homolog A (S. pombe)
SymbolCDC25A
SynonymsCDC25A2
AccessionNM_001789
Cytogenetic3p21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionCDC25A Full-Length MS Protein Standard (NP_001780), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

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