CLDN4 Full-Length MS Protein Standard


Product Description:

Name CLDN4 Full-Length MS Protein Standard
Cat# CPFL300490
Protein Nameclaudin 4
SymbolCLDN4
SynonymsCPE-R; CPER; CPETR; CPETR1; hCPE-R; WBSCR8
AccessionNM_001305
Cytogenetic7q11.23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW21.9 kDa
Expression TrueORF CloneRC200490
DescriptionCLDN4 Full-Length MS Protein Standard (NP_001296), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.

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