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GATM Full-Length MS Protein Standard

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Product Description


NameGATM Full-Length MS Protein Standard
Cat#CPFL300474
Protein Nameglycine amidinotransferase (L-arginine:glycine amidinotransferase)
SymbolGATM
SynonymsAGAT; AT; CCDS3
AccessionNM_001482
Cytogenetic15q21.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGATM Full-Length MS Protein Standard (NP_001473), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.

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