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GSK3B Full-Length MS Protein Standard

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Product Description


NameGSK3B Full-Length MS Protein Standard
Cat#CPFL300468
Protein Nameglycogen synthase kinase 3 beta
SymbolGSK3B
SynonymsGSK3beta isoform; glycogen synthase kinase-3 beta; glycogen synthase kinase 3 beta
AccessionNM_002093
Cytogenetic3q13.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGSK3B Full-Length MS Protein Standard (NP_002084), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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