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HPRT1 Full-Length MS Protein Standard

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Product Description


NameHPRT1 Full-Length MS Protein Standard
Cat#CPFL300462
Protein Namehypoxanthine phosphoribosyltransferase 1
SymbolHPRT1
SynonymsHGPRT; HPRT
AccessionNM_000194
CytogeneticXq26.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionHPRT1 Full-Length MS Protein Standard (NP_000185), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.

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