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HSD17B4 Full-Length MS Protein Standard

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Product Description


NameHSD17B4 Full-Length MS Protein Standard
Cat#CPFL300460
Protein Namehydroxysteroid (17-beta) dehydrogenase 4
SymbolHSD17B4
SynonymsDBP; MFE-2; MPF-2; PRLTS1; SDR8C1
AccessionNM_000414
Cytogenetic5q21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionHSD17B4 Full-Length MS Protein Standard (NP_000405), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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