NCK2 Full-Length MS Protein Standard


Product Description:

Name NCK2 Full-Length MS Protein Standard
Cat# CPFL300449
Protein NameNCK adaptor protein 2
SymbolNCK2
SynonymsGRB4; NCKbeta
AccessionNM_001004720
Cytogenetic2q12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW42.7 kDa
Expression TrueORF CloneRC200449
DescriptionNCK2 Full-Length MS Protein Standard (NP_001004720), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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