TSSC1 Full-Length MS Protein Standard


Product Description:

Name TSSC1 Full-Length MS Protein Standard
Cat# CPFL300409
Protein Nametumor suppressing subtransferable candidate 1
SymbolTSSC1
SynonymsD12Ertd604e; tumor suppressing subtransferable candidate 1
AccessionNM_003310
Cytogenetic2p25.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW43.4 kDa
Expression TrueORF CloneRC200409
DescriptionTSSC1 Full-Length MS Protein Standard (NP_003301), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene has been reported in PMID 9403053 as one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alignment of this gene to genomic sequence data suggests that this gene resides on chromosome 2 rather than chromosome 11.

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