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EZR Full-Length MS Protein Standard

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Product Description


NameEZR Full-Length MS Protein Standard
Cat#CPFL300404
Protein NameEZR ezrin
SymbolEZR
SynonymsCVIL; CVL; HEL-S-105; VIL2
AccessionNM_003379
Cytogenetic6q25.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionEZR Full-Length MS Protein Standard (NP_003370), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

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