EZR Full-Length MS Protein Standard


Product Description:

Name EZR Full-Length MS Protein Standard
Cat# CPFL300404
Protein NameEZR ezrin
SymbolEZR
SynonymsCVIL; CVL; HEL-S-105; VIL2
AccessionNM_003379
Cytogenetic6q25.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW69.2 kDa
Expression TrueORF CloneRC200404
DescriptionEZR Full-Length MS Protein Standard (NP_003370), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

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