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KARS Full-Length MS Protein Standard

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Product Description


NameKARS Full-Length MS Protein Standard
Cat#CPFL300311
Protein Namelysyl-tRNA synthetase
SymbolKARS
SynonymsCMTRIB; DFNB89; KARS1; KARS2; KRS
AccessionNM_005548
Cytogenetic16q23.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionKARS Full-Length MS Protein Standard (NP_005539), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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