LSM1 Full-Length MS Protein Standard


Product Description:

Name LSM1 Full-Length MS Protein Standard
Cat# CPFL300288
Protein NameLSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
SymbolLSM1
SynonymsCASM; YJL124C
AccessionNM_014462
Cytogenetic8p11.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW15.6 kDa
Expression TrueORF CloneRC200288
DescriptionLSM1 Full-Length MS Protein Standard (NP_055277), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

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