NUDT5 Full-Length MS Protein Standard


Product Description:

Name NUDT5 Full-Length MS Protein Standard
Cat# CPFL300204
Protein Namenudix (nucleoside diphosphate linked moiety X)-type motif 5
SymbolNUDT5
SynonymshYSAH1; YSA1; YSA1H; YSAH1
AccessionNM_014142
Cytogenetic10p14
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW24.1 kDa
Expression TrueORF CloneRC200204
DescriptionNUDT5 Full-Length MS Protein Standard (NP_054861), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors.

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