NDE1 Full-Length MS Protein Standard


Product Description:

Name NDE1 Full-Length MS Protein Standard
Cat# CPFL300179
Protein NamenudE nuclear distribution gene E homolog 1 (A. nidulans)
SymbolNDE1
SynonymsHOM-TES-87; LIS4; MHAC; NDE; NUDE; NUDE1
AccessionNM_017668
Cytogenetic16p13.11
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW37.5 kDa
Expression TrueORF CloneRC200179
DescriptionNDE1 Full-Length MS Protein Standard (NP_060138), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants.

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