DUS2 Full-Length MS Protein Standard


Product Description:

Name DUS2 Full-Length MS Protein Standard
Cat# CPFL300175
Protein Namedihydrouridine synthase 1-like (S. cerevisiae)
SymbolDUS2
SynonymsDUS2L; SMM1; URLC8
AccessionNM_017803
Cytogenetic16q22.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW54.9 kDa
Expression TrueORF CloneRC200175
DescriptionDUS2L Full-Length MS Protein Standard (NP_060273), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene.

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