GEMIN8 Full-Length MS Protein Standard


Product Description:

Name GEMIN8 Full-Length MS Protein Standard
Cat# CPFL300165
Protein Namegem (nuclear organelle) associated protein 8
SymbolGEMIN8
SynonymsFAM51A1
AccessionNM_001042479
CytogeneticXp22.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW28.5 kDa
Expression TrueORF CloneRC200165
DescriptionGEMIN8 Full-Length MS Protein Standard (NP_001035944), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene.

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