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DYNLRB1 Full-Length MS Protein Standard

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Product Description


NameDYNLRB1 Full-Length MS Protein Standard
Cat#CPFL300051
Protein Namedynein, light chain, roadblock-type 1
SymbolDYNLRB1
SynonymsBITH; BLP; DNCL2A; DNLC2A; ROBLD1
AccessionNM_014183
Cytogenetic20q11.21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionDYNLRB1 Full-Length MS Protein Standard (NP_054902), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18.

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