F11R Full-Length MS Protein Standard


Product Description:

Name F11R Full-Length MS Protein Standard
Cat# CPFL300004
Protein NameF11 receptor
SymbolF11R
SynonymsJAM, KAT, JAM1, JAMA, JCAM, CD321, JAM-1, JAM-A, PAM-1
AccessionNM_144504
Cytogenetic1q21.2-q21.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW29.8 kDa
Expression TrueORF CloneRC200004
DescriptionF11R Full-Length MS Protein Standard (NP_653087), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5 alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

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