Name | [DArg1, DTrp5,7,9, Leu11] Substance P, MS Grade Peptide |
Cat# | CPAP0214 |
Description | This substance P analog is a very potent broad-spectrum neuropeptide inhibitor for small cell lung cancer (SCLC) cell growth in vitro (IC50 = 5 mM). Moreover it potently inhibited signal transduction pathways in vitro and significantly delayed the growth of an SCLC xenograft in vivo. It could therefore be of therapeutic value in SCLC. |
Chemical Formula | C81H110N20O12 |
Molecular Weight | 1555.9 |
Sequence | DArg-Pro-Lys-Pro-DTrp-Gln-DTrp-Phe-DTrp-Leu-Leu-NH2 |
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