| Name | H-Cys-Val-2-Nal-Met-OH, MS Grade Peptide |
|---|---|
| Cat# | CPAP0208 |
| CAS# | 158022-12-9 |
| Description | Disruption of the function of the Ras oncogene represents a target in the search of anticancer agents. This peptidomimetic derivative is the most potent synthetic inhibitor of p21ras farnesyltransferase (Ftase). It inhibited rat brain Ras Ftase activity in a dosedependent manner with an IC50 value of 12 nM. Aromatic ring replacement by naphthylalanine maintained the intrinsic potency. |
| Chemical Formula | C26H36N4O5S2 |
| Molecular Weight | 548.73 |
| Sequence | Cys-Val-2-Nal-Met |
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