Description
Endoproteinase Arg-C (Clostripain) is a sulfhydryl proteinase associated with collagenase and isolated from Clostridium histolyticum. Endoproteinase Arg-C is highly purified, resulting in a product suitable for proteomics work. In 50 mM NH4HCO3 digestion buffer (pH 8.0), Arg-C specifically cleaves peptide bonds at the carboxyl side of arginine residues. Arg-C is used in proteomics for peptide mapping and protein sequence work due to its highly specific cleavage of peptides resulting in a limited number of fragments.
