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Decanoyl-Arg-Val-Lys-Arg-chloromethylketone MS Grade peptide


Product Description

NameDecanoyl-Arg-Val-Lys-Arg-chloromethylketone MS Grade peptide
Molecular Weight744.4 Da
Chemical FormulaC34H66ClN11O5
DescriptionPeptidyl chloromethylketone that binds to the catalytic site of furin and thus inhibits cleavage and fusion activity of viral glycoproteins, as well as virus replication. This compound also decreases the production of b-amyloid-induced active matrix metalloproteinase 2 in U87 cells. Furthermore, other than furin N-1505 the protein also inhibited the proprotein convertases PC7/LPC, PACE4, and PC6 (W.Garten, personal communication).

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