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DABCYL-TNF-a-EDANS (-4 to +6) MS Grade peptide

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Product Description


NameDABCYL-TNF-a-EDANS (-4 to +6) MS Grade peptide
Cat#CPWHB102016
SynonymsInquiry
DescriptionTACE FRET substrate I that is derived from the cleavage sequence of pro-TNFa recognized by the TNFa-cleaving enzyme (TACE). TNFa is presumably shed from cell membranes by TNFa-cleaving enzyme (TACE). Incubation of the TACE substrate with recombinant human TACE gives a specific cleavage to restore the quenched fluorescence. The substrate is widely used to screen inhibitors of TNF-convertase.
Chemical FormulaC70H104N22O18S1
Molecular Weight1573.8 Da
SequenceDABCYL-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-EDANS

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