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[DArg1, DTrp5,7,9, Leu11] Substance P, MS Grade Peptide

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Product Description


Name[DArg1, DTrp5,7,9, Leu11] Substance P, MS Grade Peptide
Cat#CPAP0214
DescriptionThis substance P analog is a very potent broad-spectrum neuropeptide inhibitor for small cell lung cancer (SCLC) cell growth in vitro (IC50 = 5 mM). Moreover it potently inhibited signal transduction pathways in vitro and significantly delayed the growth of an SCLC xenograft in vivo. It could therefore be of therapeutic value in SCLC.
Chemical FormulaC81H110N20O12
Molecular Weight1555.9
SequenceDArg-Pro-Lys-Pro-DTrp-Gln-DTrp-Phe-DTrp-Leu-Leu-NH2

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